TB-500 · Thymosin β4 · Research-Grade

TB-500 Research Peptide

A synthetic form of Thymosin Beta-4, independently tested in the United States to research-grade standards — 99%+ verified purity, lyophilized, and shipped with a Certificate of Analysis on every batch.

Newbridge Peptides TB-500 10mg research vial
99%+
Verified Purity
10mg
Per Vial
Lyo.
Powder Form
COA
Every Batch
Compound Overview

About TB-500

TB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid peptide found across a wide range of mammalian tissues and cell types. It is one of the principal actin-sequestering molecules in the body, binding monomeric G-actin and participating in the regulation of the cellular cytoskeleton.

Because of this role, TB-500 is widely used in laboratory research examining actin dynamics, cell migration, and tissue-remodeling models. Every batch we supply is sourced from vetted manufacturing partners and independently verified in the U.S. for identity and purity before it reaches your bench.

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Areas of Study

Research Applications

Reported in the scientific literature and studied in laboratory research settings. Descriptions below reflect areas of investigation, not claims of effect.

Actin Regulation

Investigated as a G-actin sequestering peptide in studies of cytoskeletal dynamics and actin-monomer balance within cell models.

Cell Migration

Examined in in-vitro models exploring cellular migration, endothelial behavior, and the mechanics of tissue movement.

Tissue-Remodeling Models

Studied in laboratory research related to tissue regeneration, remodeling, and repair pathways at the cellular level.

Product Data

Specifications

Verified against the Certificate of Analysis for lot NB-7308120 — independently tested by Horizon Analytical (USA).

CompoundTB-500 (Thymosin Beta-4)
CAS Number77591-33-4
PubChem CID16132341
Molecular FormulaC212H350N56O78S
Molecular Weight≈ 4963 g/mol
Sequence Length43 amino acids
Purity> 98% (UPLC-MS) · 99.12% this lot
AppearanceWhite to off-white lyophilized powder
SolubilitySoluble in water / bacteriostatic water
Vial Size10 mg
StorageLyophilized: −20°C · Reconstituted: 2–8°C, protect from light
Batch Verified

Certificate of Analysis

Lot NB-7308120, independently tested by Horizon Analytical in the United States. Full reports are available below.

LotNB-7308120
Tested ByHorizon Analytical · USA
AnalyzedFeb 2026
PubChem CID16132341
TestSpecificationResult
IdentityTB-500Confirmed
Quantity10 mg9.68 mg
Purity (UPLC-MS)> 98%99.12%
Endotoxin< 0.05 EU/mL
Quality Assurance

Independently Verified

Every batch undergoes independent third-party analytical testing in the United States prior to distribution.

UPLC & Mass Spectrometry

Ultra-high-performance liquid chromatography and mass spectrometry confirm peptide identity and purity to research-grade standards.

Identity & Structure

Structural confirmation ensures every vial matches its intended formulation and stated specifications.

Endotoxin & Contamination

Endotoxin, sterility, and heavy-metal screening are performed on every batch before it ships.

For laboratory and research use only. This product is not for human or veterinary use, and is not a drug, food, or cosmetic. It is not intended to diagnose, treat, cure, or prevent any disease. Handling should be performed only by qualified individuals in an appropriate laboratory environment.

Our Promise

Trusted by Researchers

Researchers rely on product consistency and verified purity to conduct meaningful work. From our home base in Virginia Beach, every batch of TB-500 is backed by U.S.-based quality assurance and a Certificate of Analysis — dependable, research-grade material you can confidently trust.

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IMPORTANT: Research Use Only

By entering this website, you acknowledge that all products sold by Newbridge Peptides are intended strictly for research purposes only. They are not for human or animal consumption, medical use, or any use not permitted by applicable law.